Oligomerization of p62 allows for selection of ubiquitinated cargo

p62 com  p62-gels are not simple substrates for autophagy but serve as platforms for both autophagosome formation and anti-oxidative stress  p62 lck ligand (zeta-interacting protein ) is a cytoplasmic protein that binds to the SH2 domain of lck in the absence

Detects Sequestosome-1 using this rabbit polyclonal Anti-phospho-p62 , Cat No ABC2047, is a rabbit polyclonal antibody that detects p62 Here, we show that the CUL5–ASB6 complex is a ubiquitin E3 ligase complex mediating p62 ubiquitination and degradation

In this study, we report that polymerization of the polyubiquitin-binding protein p62SQSTM1 yields protein bodies that either reside free in the cytosol and This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B signaling pathway The protein functions