p62 Is Up-Regulated in Cardiac Proteinopathy and Facilitates Aggresome Formation and Autophagy Activation Recently, p62 is purported to act as
We showed that endogenous p62 forms gel-like structures, which serve as platforms for autophagosome formation and nuclear factor erythroid 2-related factor 2 ( In this review, we discuss how selective autophagy is regulated An important level of regulation is the selection of proteins or organelles for degradation
roman 168 The p62 protein, also called sequestosome 1 , is a ubiquitin-binding scaffold protein that colocalizes with ubiquitinated protein aggregates in many Suppression of autophagy causes p62 accumulation and thereby contributes to tumorigenesis Here we demonstrate that autophagy deficiency promotes cell
