Oligomerization of p62 allows for selection of ubiquitinated cargo

Protein levels of exogenous CRYAA in GS iLECs after 24 hours of low-temperature rewarming Effect of 3MA+NH4Cl on p62 protein

Our results show that using such mechanisms, p62 filaments can be critical for cargo uptake in autophagy and are an integral part of phase-separated p62 bodies

p62 c0m used the proximity ligation assay to reveal that p62 and the proteasome are co-localized in situ under basal conditions They also found

p62 c0m p62 is an unstable protein that is likely governed by CRL E3 ligase complexes Moreover, knockdown of CUL5 could upregulate endogenous p62 protein level and co